Selected Publications
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Ong-Abdullah, M., Ordway, J.M., Nan J., Ooi, S.E., Kok, S.Y., Sarpan N., Azimi, N., Hashim, A.T., Zamzuri, I., Rosli S.K., Malike, F.A., Abu Bakar, N.A., Marjuni, M., Abdullah, N., Yaakub, Z., Amiruddin M.D., Nookiah, R; Singh, R., Low, E.T.L., Chan, K-L., Norazah, A., Smith, S.W., Bacher, B., Budiman, M.A., Van Brunt, A., Wischmeyer, C., Beil M., Hogan, M., Lakey, N., Lim, C. C., Arulandoo, X., Wong, C.K., Choo, C. N., Wong W. C., Kwan Y.Y., Syed Alwee,S.S.R., Sambanthamurthi, R. & Martienssen, RA (2015). Loss of Karma transposon methylation underlies the mantled somaclonal variant of oil palm. Nature 525: 533–537
Impact Factor: 49.962
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Singh, R., Ong-Abdullah, M., Low, E.T.L., Abdul Manaf, M.A., Rosli, R., Rajanaidu, N., Ooi, L C-L., Ooi, S.E., Chan, K.L., Halim, M.A., Azizi, N., Jayanthi, N., Bacher, B., Lakey, N., Smith, S W., He, D., Hogan, M., Budiman, M.A., Lee, E. K., Desalle, R., Kudrna, D., Goicoechea, J. L.,Wing, R. A., Wilson, R.K., Fulton, R.S., Ordway, J.M., Martienssen, R.A. and Sambanthamurthi, R. (2013). Oil palm genome sequences reveals divergence of interfertile species in old and new worlds. Nature 500(7462): 335-339
Impact Factor: 49.962
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Singh, R., Low, E-T L., Ooi, L C-L., Ong-Abdullah, M.,Ting, N-C., Jayanthi, N., Rajanaidu, N., Amiruddin, M D., Rosli, R., Abdul Manaf, M A., Chan, K L., Halim, M A., Azizi, N., Lakey, N., Smith, S W., Budiman, M A., Hogan, M., Bacher, B., Brunt, A V.,Wang, C., Ordway, J M., Sambanthamurthi, R. and Martienssen, R A. (2013). The Oil Palm Shell Gene Controls Oil Yield And Encodes A Homologue Of Seedstick. Nature 500(7462): 340-344
Impact Factor: 49.962
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Sambanthamurthi, R., Sundram K., and Tan, Y.A. (2000). Chemistry and biochemistry of palm oil. Progress in Lipid Research 39: 507-558
Impact Factor: 16.195
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Singh, R., Low, E. T. L., Ooi, L.C-L., Ong-Abdullah, M., Rajanaidu, N., Ting, N-C., Marhalil, M., Chan,P-L.,Maizura,I.,Abdul M.,Jayanthi, N., Chan, K-L., Rozana, R., Mohd Amin, H., Norazah, A., Budiman., L., Bacher, B.,Van Brunt, A., Wang, C., Hogan.,.,Jill, D., MacDonaldD.,Smith.,Ordway., MartienssenSambanthamurthi(2014). The oil palm VIRESCENS gene controls fruit colour and encodes a R2R3-MYB. Nature Communications doi :10. 1038 /ncomms51
Impact Factor: 14.919
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Singh, R., Low, E.T., Ooi L.C-L., Abdullah, M.O., Ting, N-C., Nookiah, R., Ithnin,M., Marjuni, M.,Mustaffa, S., Yaakub, Z., Amiruddin, M.D., Manaf, M.A., Chan, K.L., Ab Halim, M.A., Nik Mohd Sanusi, N.S., Lakey, N., Sachdeva,M., Bacher, B., Garner, P. A., Jill D., MacDonald, J.D., Smith. S., Wischmeyer, C., Budiman, M.A., Beil, M., Stroff, C., Reed, J., Van Brunt, A., Berg, H., Ordway, J.M. and Sambanthamurthi, R. (2020) Variation for heterodimerization and nuclear localization among known and novel oil palm SHELL alleles. The New Phytologist. 226(2):426-440. doi: 10.1111/nph.
Impact Factor: 10.323
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Sambanthamurthi, R., Chong, C.L., Oo, K.C., Yeo, K. H. and Rajan, P. (1991). Chilling-induced lipid hydrolysis in the oil palm (Elaeis guineensis) mesocarp. J. Exp. Bot. 42:1199-1205
Impact Factor: 6.992
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Leow, S. S., Sekaran, S. D., Sundram, K., Tan, Y. A., & Sambanthamurthi, R. (2013). Oil palm phenolics attenuate changes caused by an atherogenic diet in mice. European Journal of Nutrition. 52(2): 443-456. DOI: 10.1007/s00394-012-0346-0
Impact Factor: 5.614
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Conlon, M.A., Sambanthamurthi, R., Tan, Y.A., Sundram, K., Fairus, S., Abeywardena, M.Y. (2020). Consumption of an oil palm fruit extract promotes large bowel health in rats. Nutrients. 12(3):644. doi:10.3390/nu12030644 Impact Factor: 5.429
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Fairus, S., Leow, S.S., Mohamed, I. N., Tan, Y.A., Sundram, K. and Sambanthamurthi, R. (2018). A phase I single-blind clinical trial to evaluate the safety of oil palm phenolics (OPP) supplementation in healthy volunteers. Scientific Reports 8:8217 doi:10.1038/s41598-018-26384-7
Impact Factor: 4.996
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Leow, S. S., Sekaran, S. D., Tan, Y. A., Sundram, K., & Sambanthamurthi, R. (2013). Oil palm phenolics confer neuroprotective effects involving mouse cognitive and motor functions. Nutritional Neuroscience. 16(5): 207-217. doi: 10.1179/1476830512Y.0000000047
Impact Factor: 4.994
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Sambanthamurthi, R., Oo, K.C. and Ong, A.S.H. (1987). Lipid metabolism in oil palm (Elaeis guineensis and Elaeis oleifera) protoplasts. Plant Science 5: 97-105.
Impact Factor: 4.729
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Parveez, G.K.A., Rasid, O.A., Masani, M.Y. and Sambanthamurthi, R.(2015). Biotechnology of oil palm: strategies towards manipulation of lipid content and composition. Plant Cell Rep. 34:533-43. doi: 10.1007/s00299-014-1722-4.
Impact Factor: 4.57
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Patten, G.S., Abeywardena, M.Y., Sundram K., Tan, Y.A. and Sambanthamurthi, R. (2015) Effect of palm oil phenolics on gastrointestinal transit, contractility and motility in the rat. Journal of Functional Foods. 17:928–937
Impact Factor: 4.451
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Che Idris, C. A., Karupaiah, T., Sundram, K., Tan, Y. A., Balasundram, N., Leow, S. S., Nasruddin, N. S., & Sambanthamurthi, R. (2014). Oil palm phenolics and vitamin E reduce atherosclerosis in rabbits. Journal of Functional Foods. doi: 10.1016/j.jff.2014.01.002
Impact Factor: 4.451
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Sambanthamurthi, R., Oo, K.C. and Parman, S.H. (1995). Factors affecting lipase activity in Elaeis guineensis mesocarp. Plant Physiology and Biochemistry. 33: 353-359*
Impact Factor: 4.27
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Leow, S. S., Luu,A., Shrestha,S., Hayes, K.C. and Sambanthamurthi, R. (2018) Drosophila larvae fed palm fruit juice (PFJ) delay pupation via expression regulation of hormetic stress response genes linked to ageing and longevity. Experimental Gerontology 106 198–221
Impact Factor: 4.032
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Leow, S. S., Sekaran, S. D., Sundram, K., Tan, Y. A., & Sambanthamurthi, R. (2011). Differential transcriptomic profiles effected by oil palm phenolics indicate novel outcomes. BMC Genomics. 12(432). doi: 10.1186/1471-2164-12-432 *
Impact Factor: 3.969
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Sambanthamurthi, R., Tan, Y. A., Sundram, K., Hayes, K. C., Abeywardena, M., Leow, S. S., Sekaran, S. D., Sambandan, T. G., Rha, C., Sinskey, A. J., Subramaniam, K., Fairus, S., & Wahid, M. B. (2011). Positive outcomes of oil palm phenolics on degenerative diseases in animal models. British Journal of Nutrition. 106(11): 1664-1675. DOI: 10.1017/S0007114511002133
Impact Factor: 3.718
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Sambanthamurthi, R., Tan, Y. A., Sundram, K., Abeywardena, M., Sambandan, T. G., Rha, C., Sinskey, A. J., Subramaniam, K., Leow, S. S., Hayes, K. C., & Wahid, M. B. (2011). Oil palm vegetation liquor: A new source of phenolic bioactives. British Journal of Nutrition. 106(11): 1655-1663. doi: 10.1017/S0007114511002121
Impact Factor: 3.718
All Publications
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Low, E. L., Chan, K. L., Zaki, N. M., Taranenko, E., Ordway, J. M., Wischmeyer, C., Buntjer, J., Halim, M. A. A., Sanusi, N. S. N. M., Nagappan, J., Rosli, R., Bondar, E., Amiruddin, N., Sarpan, N., Ting, N. C., Chan, P. L., Ong-Abdullah, M., Marjuni, M., Mustaffa, S., Abdullah, N., … Singh, R. (2024). Chromosome-scale Elaeis guineensis and E. oleifera assemblies: comparative genomics of oil palm and other Arecaceae. G3 (Bethesda, Md.), 14(9), jkae135. https://doi.org/10.1093/g3journal/jkae135
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Leow, S. S., Khoo, J. S., Lee, W. K., Hoh, C. C., Fairus, S., Sambanthamurthi, R., & Hayes, K. C. (2024). RNA-Seq transcriptome profiling of Nile rat livers reveals novel insights on the anti-diabetic mechanisms of Water-Soluble Palm Fruit Extract. Journal of applied genetics, 10.1007/s13353-024-00880-1. Advance online publication. https://doi.org/10.1007/s13353-024-00880-1
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Leow, S. S., Khoo, J. S., Ng, S. M., Lee, W. K., Hoh, C. C., Fairus, S., Sambanthamurthi, R., & Hayes, K. C. (2023). Insulin and circadian rhythm genes of the Nile rat (Arvicanthis niloticus) are conserved and orthologous to those in the rat, mouse and human. Genetica, 10.1007/s10709-023-00202-z. Advance online publication. https://doi.org/10.1007/s10709-023-00202-z
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Ooi, L. C. L., Kamil, N.A., Mohd Salleh, K., Low, E. T. L., Ong-Abdullah, M., Lakey, N., Ordway, J.M., Garner, P.A., Nookiah, R., Sambanthamurthi, R., Manaf, M. A, Azman, I. and Singh, R. (2023) Improving oil palm sustainability with molecular-precision agriculture: yield impact of SHELL DNA testing in the Malaysian oil palm supply chain, Scientia Horticulturae. https://doi.org/10.1016/j.scienta.2023.112305
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Ting, N.C., Ordway, J.M., van de Weg, E., Serdari, N.M., Low, L., Mustaffa, S., Wischmeyer, C., Smulders, M. J. M., Sambanthamurthi, R. and Singh, R. (2023). Development and applications of the Oil Palm 78K Infinium®️ HD SNP Array for linkage analysis and chromosome scanning. Scientia Horticulturae. https://doi.org/10.1016/j.scienta.2023.112104
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Singh, R., Kamil, N.N., Ooi, L., Low, L., Ong-Abdullah, M., Sambanthamurthi, R., Lakey, N., Manaf, M. A. and Azman, I. (2022). SHELL Genetic Testing: A Key Enabler of Yield Improvement and Sustainable Palm Oil Production. The Planter. 98. 10.56333/tp.2022.011
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Leow, S. S., Fairus, S., and Sambanthamurthi, R (2022). Investigating the potential anti-diabetic mechanisms of water-soluble palm fruit extract. Journal of Oil Palm Research, https://doi.org/10.21894/jopr.2022.0001
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Singh, R., Ooi, L. CL., Ting, N.C., Low, E.-T. L., Abdullah, M. O., Nookiah, R., Marjuni, M., Mustaffa, S., Manaf, M. A. A., Garner, P. A., Reed, J., Wischmeyer, C., Beil, M., Bacher, B., Lakey,N., Ordway, J. M. and Sambanthamurthi, R. (2021) A genetic platform for predicting and reducing non-tenera contamination in oil palm (Elaeis guineensis) seed supply. Tree Genetics & Genomes 17, 45. https://doi.org/10.1007/s11295-021-01527-6
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Leow, S. S., Fairus, S., and Sambanthamurthi, R. (2021). Water-soluble palm fruit extract: Composition, biological properties, and molecular mechanisms for health and non-health applications. Critical Reviews in Food Science and Nutrition, 1–17. https://doi.org/10.1080/10408398.2021.1939648
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Zolkafli, S. H., Ting, N.-C., Nik Mohd Sanusi, N. S., Ithnin, M., Mayes, S., Massawe, F., Sambanthamurthi, R., Ismail, I., Zainol Abidin, M. I., Roowi, S. H., Lee, Y. P., Hanafi, N. F. F., and Singh, R. (2021). Comparison of quantitative trait loci (QTLs) associated with yield components in two commercial Dura × Pisifera breeding crosses. Euphytica, 217(6), 104–104. https://doi.org/10.1007/s10681-021-02825-9
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Leow, S. S., Fairus, S., and Sambanthamurthi, R. (2021). Inhibition of cholinesterases by water-soluble palm fruit extract. Journal of Oil Palm Research, https://doi.org/10.21894/jopr.2021.0028
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Singh, R., Lee, K. T., Ooi, L. C. L., Low, E. T. L., Abdullah, M. O., Sambanthamurthi, R., and Azman, I. (2021). An overview of the development of the oil palm industry and impact of the shell gene innovation as a quality control tool to improve productivity. Journal of Oil Palm Research, https://doi.org/10.21894/jopr.2020.0115
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Ting, N.-C., Mayes, S., Massawe, F., Sambanthamurthi, R., Chan, K.-L., Sritharan, K., and Singh, R. (2021). Candidate genes linked to QTL regions associated with fatty acid composition in oil palm. Biologia, 76(1), 267–279. https://doi.org/10.2478/s11756-020-00563-2
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Leow, S. S., Lee, W.-K., Khoo, J.-S., Teoh, S., Hoh, C.-C., Fairus, S., Sambanthamurthi, R., and Hayes, K. C. (2020). Identification of reference genes for real-time polymerase chain reaction gene expression studies in Nile rats fed Water-Soluble Palm Fruit Extract. Molecular Biology Reports, 47(12), 9409–9427. https://doi.org/10.1007/s11033-020-06003-3
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Ramli, U. S., Tahir, N. I., Rozali, N. L., Othman, A., Muhammad, N. H., Muhammad, S. A., Tarmizi, A. H. A., Hashim, N., Sambanthamurthi, R., Singh, R., Manaf, M. A. A., and Parveez, G. K. A. (2020). Sustainable Palm Oil—The Role of Screening and Advanced Analytical Techniques for Geographical Traceability and Authenticity Verification. Molecules, 25(12), 2927. https://doi.org/10.3390/molecules25122927
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Ting, N.-C., Sherbina, K., Khoo, J.-S., Kamaruddin, K., Chan, P.-L., Chan, K.-L., Halim, M. A. A., Sritharan, K., Yaakub, Z., Mayes, S., Massawe, F., Chang, P. L., Nuzhdin, S. V., Sambanthamurthi, R., and Singh, R. (2020). Expression of fatty acid and triacylglycerol synthesis genes in interspecific hybrids of oil palm. Scientific Reports, 10(1), 16296. https://doi.org/10.1038/s41598-020-73170-5
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Singh, R., Low, E.-T. L., Ooi, L. C.-L., Ong-Abdullah, M., Ting, N.-C., Nookiah, R., Ithnin, M., Marjuni, M., Mustaffa, S., Yaakub, Z., Amiruddin, M. D., Manaf, M. A. A., Chan, K.-L., Halim, M. A. A., Sanusi, N. S. N. M., Lakey, N., Sachdeva, M., Bacher, B., Garner, P. A., … Sambanthamurthi, R. (2020). Variation for heterodimerization and nuclear localization among known and novel oil palm SHELL alleles. New Phytologist, 226(2), 426–440. https://doi.org/10.1111/nph.16387 *
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Conlon, M. A., Sambanthamurthi, R., Tan, Y. A., Sundram, K., Fairus, S., and Abeywardena, M. Y. (2020). Consumption of an Oil Palm Fruit Extract Promotes Large Bowel Health in Rats. Nutrients, 12(3), E644. https://doi.org/10.3390/nu12030644 *
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Ramli, U. S., Tahir, N. I., Rozali, N. L., Othman, A., Muhammad, N. H., Muhammad, S. A., Tarmizi, A. H. A., Hashim, N., Sambanthamurthi, R., Singh, R., Manaf, M. A. A., and Parveez, G. K. A. (2020). Sustainable Palm Oil—The Role of Screening and Advanced Analytical Techniques for Geographical Traceability and Authenticity Verification. Molecules, 25(12), 2927. https://doi.org/10.3390/molecules25122927
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Ramli, U. S., Othman, A., Lau, Y. C. B., Tahir, N. I., Syahanim, S., Zain, N., Rozali, N. L., Hassan, H., Mohd Ishak, N., Balqis, S., Dzulkafli, S. B., Singh, R., Rashid, O. A., Sambanthamurthi, R., Manaf, M. A., and Parveez, G. K. A. (2020). Omics platform technologies for discovery and understanding the systems biology of oil palm. Journal of Oil Palm Research, https://doi.org/doi.org/10.21894/jopr.2020.0084
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Amiruddin, N., Chan, P.-L., Azizi, N., Morris, P., Chan, K.-L., Ong, P.W., Rosli,R., Masura S.S., Murphy, D.J., Sambanthamurthi, R., Haslam, R. Chye, M.-L., Harwood, J. and Low, E.-T. L. (2020) Characterization of Oil Palm Acyl-CoA-Binding Proteins and Correlation of Their Gene Expression with Oil Synthesis. Plant and Cell Physiology, Volume 61, Issue 4, April 2020, Pages 735–747, https://doi.org/10.1093/pcp/pcz237
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Weinberg, R. P., Koledova, V. V., Subramaniam, A., Schneider, K., Artamonova, A., Sambanthamurthi, R., Hayes, K. C., Sinskey, A. J., and Rha, C. (2019). Palm Fruit Bioactives augment expression of Tyrosine Hydroxylase in the Nile Grass Rat basal ganglia and alter the colonic microbiome. Scientific Reports, 9(1), 18625. https://doi.org/10.1038/s41598-019-54461-y
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Ooi, L. C. L., Low, E. T., Ordway, J. M., Marjuni, M., Yaakub, Z., Jiang, N., Smith, S., Bacher, B., Garner, P. A., Leinenger, M. T., Sander, N., Chan, P. L., Ong, P. W., Abdullah, M. O., Nookiah, R., Manaf, M. A., Lakey, N., Sambanthamurthi, R., and Singh, R. (2019). SureSawitTM True-To-Type—A high throughput universal single nucleotide polymorphism (SNP) panel for DNA fingerprinting, purity testing and origin verification in oil palm. Journal of Oil Palm Research, 31(4), 561–571. https://doi.org/10.21894/jopr.2019.0048
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Othman, A., Goggin, K. A., Tahir, N. I., Brodrick, E., Singh, R., Sambanthamurthi, R., Parveez, G. K. A., Davies, A. N., Murad, A. J., Muhammad, N. H., Ramli, U. S., and Murphy, D. J. (2019). Use of headspace-gas chromatography-ion mobility spectrometry to detect volatile fingerprints of palm fibre oil and sludge palm oil in samples of crude palm oil. BMC Research Notes, 12(1), 229. https://doi.org/10.1186/s13104-019-4263-7
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Weinberg, R. P., Koledova, V. V., Schneider, K., Sambandan, T. G., Grayson, A., Zeidman, G., Artamonova, A., Sambanthamurthi, R., Fairus, S., Sinskey, A. J., and Rha, C. (2018). Palm Fruit Bioactives modulate human astrocyte activity in vitro altering the cytokine secretome reducing levels of TNFα, RANTES and IP-10. Scientific Reports, 8(1), 16423. https://doi.org/10.1038/s41598-018-34763-3
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Fairus, S., Leow, S.-S., Mohamed, I. N., Tan, Y.-A., Sundram, K., and Sambanthamurthi, R. (2018). A phase I single-blind clinical trial to evaluate the safety of oil palm phenolics (OPP) supplementation in healthy volunteers. Scientific Reports, 8(1), 8217. https://doi.org/10.1038/s41598-018-26384-7 *
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Leow, S. S., Luu, A., Shrestha, S., Hayes, K. C., and Sambanthamurthi, R. (2018). Drosophila larvae fed palm fruit juice (PFJ) delay pupation via expression regulation of hormetic stress response genes linked to ageing and longevity. Experimental Gerontology, 106, 198–221. https://doi.org/10.1016/j.exger.2018.03.013 *
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Rosli, R., Amiruddin, N., Ab Halim, M. A., Chan, P.-L., Chan, K.-L., Azizi, N., Morris, P. E., Leslie Low, E.-T., Ong-Abdullah, M., Sambanthamurthi, R., Singh, R., and Murphy, D. J. (2018). Comparative genomic and transcriptomic analysis of selected fatty acid biosynthesis genes and CNL disease resistance genes in oil palm. PloS One, 13(4), e0194792. https://doi.org/10.1371/journal.pone.0194792
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Ting, N. C., Mayes, S., Massawe, F., Sambanthamurthi, R., Jansen, J., Alwee, S. S. R. S., Seng, T. Y., Ithnin, M., and Singh, R. (2018). Putative regulatory candidate genes for QTL linked to fruit traits in oil palm (Elaeis guineensis Jacq.). Euphytica, 214(11), 214. https://doi.org/10.1007/s10681-018-2296-y
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Weinberg, R. P., Koledova, V. V., Shin, H., Park, J. H., Tan, Y. A., Sinskey, A. J., Sambanthamurthi, R., and Rha, C. (2018). Oil Palm Phenolics Inhibit the In Vitro Aggregation of β-Amyloid Peptide into Oligomeric Complexes. International Journal of Alzheimer’s Disease, 2018, e7608038. https://doi.org/10.1155/2018/7608038
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Chan, K.-L., Tatarinova, T. V., Rosli, R., Amiruddin, N., Azizi, N., Halim, M. A. A., Sanusi, N. S. N. M., Jayanthi, N., Ponomarenko, P., Triska, M., Solovyev, V., Firdaus-Raih, M., Sambanthamurthi, R., Murphy, D., and Low, E.-T. L. (2017). Evidence-based gene models for structural and functional annotations of the oil palm genome. Biology Direct, 12(1), 21. https://doi.org/10.1186/s13062-017-0191-4
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Low, E. T. L., Jayanthi, N., Chan, K. L., Nik Shazana, N. M. S., Ab Halim, M., Rozana, R., Azizi, N., Amiruddin, N., Angel, L. P. L., Ong.Abdullah, M., Singh, R., Abd Manaf, M. A., Sambanthamurthi, R., Ghulam Kadir, A. P., and Kushairi, A. (2017). The oil palm genome revolution. Journal of Oil Palm Research, 29(4), 456–468. https://doi.org/10.21894/jopr.2017.00018
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Leow, S.-S., Bolsinger, J., Pronczuk, A., Hayes, K. C., and Sambanthamurthi, R. (2016). Hepatic transcriptome implications for palm fruit juice deterrence of type 2 diabetes mellitus in young male Nile rats. Genes and Nutrition, 11, 29. https://doi.org/10.1186/s12263-016-0545-z
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Ooi, L. C.-L., Low, E.-T. L., Abdullah, M. O., Nookiah, R., Ting, N. C., Nagappan, J., Manaf, M. A. A., Chan, K.-L., Halim, M. A., Azizi, N., Omar, W., Murad, A. J., Lakey, N., Ordway, J. M., Favello, A., Budiman, M. A., Van Brunt, A., Beil, M., Leininger, M. T., Jiang, N., Smith. S.W., Brown, C.R., Kuek, A.C., Bahrain, S., Hoynes-O'Connor, A., Nguyen, A.Y., Chaudhari, H.G., Shah, S.A., Choo, Y.M., Sambanthamurthi, R., Singh, R. (2016). Non-tenera Contamination and the Economic Impact of SHELL Genetic Testing in the Malaysian Independent Oil Palm Industry. Frontiers in Plant Science, 7, 771. https://doi.org/10.3389/fpls.2016.00771
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Ting, N.-C., Yaakub, Z., Kamaruddin, K., Mayes, S., Massawe, F., Sambanthamurthi, R., Jansen, J., Low, L. E. T., Ithnin, M., Kushairi, A., Arulandoo, X., Rosli, R., Chan, K.-L., Amiruddin, N., Sritharan, K., Lim, C. C., Nookiah, R., Amiruddin, M. D., and Singh, R. (2016). Fine-mapping and cross-validation of QTLs linked to fatty acid composition in multiple independent interspecific crosses of oil palm. BMC Genomics, 17, 289. https://doi.org/10.1186/s12864-016-2607-4
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Ong-Abdullah, M., Ordway, J. M., Jiang, N., Ooi, S.-E., Kok, S.-Y., Sarpan, N., Azimi, N., Hashim, A. T., Ishak, Z., Rosli, S. K., Malike, F. A., Bakar, N. A. A., Marjuni, M., Abdullah, N., Yaakub, Z., Amiruddin, M. D., Nookiah, R., Singh, R., Low, E.-T. L., Chan, K-L., Norazah, A., Smith, S W., Bacher, B., Budiman, M.A.,Van Brunt, A., Wischmeyer, C., Beil, M., Hogan, M., Lakey,N., Lim, C. C., Arulandoo, X., Wong, C.K., Choo, C.N., Wong W.C., Kwan Y.Y., Syed Alwee, S.S.R., Sambanthamurthi, R., and Martienssen, R. A. (2015). Loss of Karma transposon methylation underlies the mantled somaclonal variant of oil palm. Nature, 525(7570), 533–537. https://doi.org/10.1038/nature15365 *
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Osborne, A., Sanchez, J., Wangh, L., Sambanthamurthi, R., and Hayes, kc. (2015). Oxidative Damage is not a Major Contributor to AZT-Induced Mitochondrial Mutations. Journal of AIDS and Clinical Research, 6(04), 441. https://doi.org/10.4172/2155-6113.1000441
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Parveez, G. K. A., Rasid, O. A., Masani, M. Y. A., and Sambanthamurthi, R. (2015). Biotechnology of oil palm: Strategies towards manipulation of lipid content and composition. Plant Cell Reports, 34(4), 533–543. https://doi.org/10.1007/s00299-014-1722-4 *
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Patten, G. S., Abeywardena, M. Y., Sundram, K., Tan, Y. A., and Sambanthamurthi, R. (2015). Effect of oil palm phenolics on gastrointestinal transit, contractility and motility in the rat. Journal of Functional Foods, 17, 928–937. https://doi.org/10.1016/j.jff.2015.06.008 *
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Wong, Y. T., Kushairi, A., Rajanaidu, N., Osman, M., Wickneswari, R., and Sambanthamurthi, R. (2016). Screening of wild oil palm (Elaeis guineensis) germplasm for lipase activity. The Journal of Agricultural Science, 154(7), 1241–1252. https://doi.org/10.1017/S0021859615001112
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Masani, M. Y. A., Noll, G. A., Parveez, G. K. A., Sambanthamurthi, R., and Prüfer, D. (2014). Efficient transformation of oil palm protoplasts by PEG-mediated transfection and DNA microinjection. PLOS ONE, 9(5), e96831. https://doi.org/10.1371/journal.pone.0096831
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Bolsinger, J., Pronczuk, A., Sambanthamurthi, R., and Hayes, K. C. (2014). Anti-diabetic effects of palm fruit juice in the Nile rat (Arvicanthis niloticus). Journal of Nutritional Science, 3, e5. https://doi.org/10.1017/jns.2014.3
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Che Idris, C. A., Karupaiah, T., Sundram, K., Tan, Y. A., Balasundram, N., Leow, S. S., Nasruddin, N. S., and Sambanthamurthi, R. (2014). Oil palm phenolics and vitamin E reduce atherosclerosis rabbits. Journal of Functional Foods, 7, 541–550. https://doi.org/10.1016/j.jff.2014.01.002 *
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Ji, X., Usman, A., Razalli, N. H., Sambanthamurthi, R., and Gupta, S. V. (2015). Oil palm phenolics (OPP) inhibit pancreatic cancer cell proliferation via suppression of NF-κB pathway. Anticancer Research, 35(1), 97–106.
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Osborne, A. E., Sanchez, J. A., Solomon, M., Stopa, A., Wangh, L. J., Sambanthamurthi, R., and Hayes, K. C. (2014). Palm fruit juice mitigates AZT mitochondrial genotoxicity and dose- dependent cytotoxicity. Journal of AIDS and Clinical Research, 5(12). https://doi.org/10.4172/2155-6113.1000400
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Singh, R., Low, E.-T. L., Ooi, L. C.-L., Ong-Abdullah, M., Nookiah, R., Ting, N.-C., Marjuni, M., Chan, P.-L., Ithnin, M., Manaf, M. A. A., Nagappan, J., Chan, K.-L., Rosli, R., Halim, M. A., Azizi, N., Budiman, M. A., Lakey, N., Bacher, B., Van Brunt, A., Wang, C., Hogan, M., He, D., Jill, D., MacDonald, J.D., Smith, S.W., Ordway, J.M., Martienssen, R.A. and Sambanthamurthi, R. (2014). The oil palm VIRESCENS gene controls fruit colour and encodes a R2R3-MYB. Nature Communications, 5(1), 4106. https://doi.org/10.1038/ncomms5106 *
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Ting, N.-C., Jansen, J., Mayes, S., Massawe, F., Sambanthamurthi, R., Ooi, L. C.-L., Chin, C. W., Arulandoo, X., Seng, T.-Y., Alwee, S. S. R. S., Ithnin, M., and Singh, R. (2014). High density SNP and SSR-based genetic maps of two independent oil palm hybrids. BMC Genomics, 15(1), 309. https://doi.org/10.1186/1471-2164-15-309
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Masani, M. Y. A., Noll, G., Parveez, G. K. A., Sambanthamurthi, R., and Prüfer, D. (2013). Regeneration of viable oil palm plants from protoplasts by optimizing media components, growth regulators and cultivation procedures. Plant Science: An International Journal of Experimental Plant Biology, 210, 118–127. https://doi.org/10.1016/j.plantsci.2013.05.021
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Leow, S.-S., Sekaran, S. D., Sundram, K., Tan, Y., and Sambanthamurthi, R. (2013). Gene expression changes in spleens and livers of tumour-bearing mice suggest delayed inflammation and attenuated cachexia in response to oil palm phenolics. Journal of Nutrigenetics and Nutrigenomics, 6(6), 305–326. https://doi.org/10.1159/000357948
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Leow, S.-S., Sekaran, S. D., Tan, Y., Sundram, K., and Sambanthamurthi, R. (2013). Oil palm phenolics confer neuroprotective effects involving cognitive and motor functions in mice. Nutritional Neuroscience, 16(5), 207–217. https://doi.org/10.1179/1476830512Y.0000000047 *
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Leow, S.-S., Sekaran, S. D., Sundram, K., Tan, Y., and Sambanthamurthi, R. (2013). Oil palm phenolics attenuate changes caused by an atherogenic diet in mice. European Journal of Nutrition, 52(2), 443–456. https://doi.org/10.1007/s00394-012-0346-0 *
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Singh, R., Ong-Abdullah, M., Low, E.-T. L., Manaf, M. A. A., Rosli, R., Nookiah, R., Ooi, L. C.-L., Ooi, S.-E., Chan, K.-L., Halim, M. A., Azizi, N., Nagappan, J., Bacher, B., Lakey, N., Smith, S. W., He, D., Hogan, M., Budiman, M. A., Lee, E. K., Desalle, R., Kudrna, D., Goicoechea, J. L., Wing, R. A., Wilson, R. K., Fulton, R.S., Ordway, J. M., Martienssen, R. A. and Sambanthamurthi, R. (2013). Oil palm genome sequence reveals divergence of interfertile species in Old and New worlds. Nature, 500(7462), 335–339. https://doi.org/10.1038/nature12309 *
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Singh, R., Low, E.-T. L., Ooi, L. C.-L., Ong-Abdullah, M., Ting, N.-C., Nagappan, J., Nookiah, R., Amiruddin, M. D., Rosli, R., Manaf, M. A. A., Chan, K.-L., Halim, M. A., Azizi, N., Lakey, N., Smith, S. W., Budiman, M. A., Hogan, M., Bacher, B., Van Brunt, A., Wang, C; Ordway, J M; Sambanthamurthi, R. And Martienssen, R. A. (2013). The oil palm SHELL gene controls oil yield and encodes a homologue of SEEDSTICK. Nature, 500(7462), 340–344. https://doi.org/10.1038/nature12356 *
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Ramli, U. S., Sambanthamurthi, R., Rasid, O. A., Parveez, G. K. A., Abdul Manaf, M. A., Othman, A., Masani, M.Y.A., Cheah, S. C., Syed Alwee, S. S. R., Akmar, S. N. A., and Wahid, M. B. (2012). The isolation and Characterisation of oil palm (Elaeis guineensis Jacq.) -Ketoacyl-Acyl Carrier Protein (ACP) Synthase (KAS) II cDNA. Journal of Oil Palm Research, 24, 1480–1491
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Leow, S.-S., Sekaran, S. D., Sundram, K., Tan, Y., and Sambanthamurthi, R. (2011). Differential transcriptomic profiles effected by oil palm phenolics indicate novel health outcomes. BMC Genomics, 12(1), 432. https://doi.org/10.1186/1471-2164-12-432 *
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Sambanthamurthi, R., Tan, Y., Sundram, K., Hayes, K. C., Abeywardena, M., Leow, S.-S., Sekaran, S. D., Sambandan, T. G., Rha, C., Sinskey, A. J., Subramaniam, K., Fairus, S., and Wahid, M. B. (2011). Positive outcomes of oil palm phenolics on degenerative diseases in animal models. The British Journal of Nutrition, 106(11), 1664–1675. https://doi.org/10.1017/S0007114511002133 *
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Sambanthamurthi, R., Tan, Y., Sundram, K., Abeywardena, M., Sambandan, T. G., Rha, C., Sinskey, A. J., Subramaniam, K., Leow, S.-S., Hayes, K. C., and Basri Wahid, M. (2011). Oil palm vegetation liquor: A new source of phenolic bioactives. The British Journal of Nutrition, 106(11), 1655–1663. https://doi.org/10.1017/S0007114511002121 *
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Sekaran, S. D., Leow, S. S., Abobaker, N., Tee, K. K., Sundram, K., Sambanthamurthi, R., and Wahid, M. B. (2010). Effects of oil palm phenolics on tumor cells in vitro and in vivo. African Journal of Food Science, 4(8), 495–502
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Choi, D. S., Andrade, M. H. C., Willis, L. B., Cho, C., Schoenheit, J., Bocazzi, P., Sambanthamurthi, R., Sinskey, A. J., and Rha, C. K. (2008). Effect of agitation and aeration on yield optimization of oil palm suspension culture. Journal of Oil Palm Research, 1, 23–24
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Kaur, J. S., and Sambanthamurthi, R. (2008). Carotenoid profiles and preliminary investigation on carotenoid biosynthesis in the oil palm (Elaeis guineensis) mesocarp. Journal of Oil Palm Research, 2, 108–117
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Rasid, O. A., Ho, C. L., Parveez, G. K. A., Sambanthamurthi, R., and Napis, S. (2008). Plant carotenoids: Genetic engineering for high value-added products. Journal of Oil Palm Research, 21, 588–601
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Rasid, O., Syuhada, W. s, Ayub, N. H., Subhi, S., Mohamed, Z., Ho, C. L., Sambanthamurthi, R., and Napis, S. (2008). RT-PCR amplification and cloning of partial DNA sequence coding for oil palm (Elaeis oleifera) Phytoene Synthase Gene. Asia-Pacific Journal of Molecular Biology and Biotechnology, 16(1), 17–24
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Wan Omar, W. S., Willis, L. B., Rha, C. K., Sinskey, A. J., Ramli, U. S., Masani, M.Y.A., Parveez, G. K. A., and Sambanthamurthi, R. (2008). Isolation and utilization of acetyl-CoA carboxylase from oil palm (Elaeis guineensis) mesocarp. Journal of Oil Palm Research, 2, 97–107
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Willis, L. B., Wan Omar, W. S., Sambanthamurthi, R., and Sinskey, A. J. (2008). Non-radioactive assay for acetyl-CoA carboxylase activity. Journal of Oil Palm Research, 2, 30–36
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Yip, J. T., Masani, M.Y.A., Parveez, G. K. A., and Sambanthamurthi, R. (2008). Activity studies, gene characterization and manipulation of ß-ketothiolase of oil palm (Elaeis guineensis Jacq.) mesocarp. Journal of Oil Palm Research, 2, 118–133
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Tan, Y.-A., Sambanthamurthi, R., Sundram, K., and Wahid, M. B. (2007). Valorisation of palm by-products as functional components. European Journal of Lipid Science and Technology, 109(4), 380–393. https://doi.org/10.1002/ejlt.200600251
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Balasundram, N., Ai, T. Y., Sambanthamurthi, R., Sundram, K., and Samman, S. (2005). Antioxidant properties of palm fruit extracts. Asia Pacific Journal of Clinical Nutrition, 14(4), 319–324
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Sundram, K., Sambanthamurthi, R., and Tan, Y. A. (2003). Palm fruit chemistry and nutrition. Asia Pacific Journal of Clinical Nutrition, 12(3), 355–362
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Sambanthamurthi, R., Sundram, K., and Tan, Y. (2000). Chemistry and biochemistry of palm oil. Progress in Lipid Research, 39(6), 507–558. https://doi.org/10.1016/s0163-7827(00)00015-1 *
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Akmar, S. N. A., Cheah, S. C., Aminah, S., Ooi, C. L., Sambanthamurthi, R., and Murphy, D. J. (1999). Characterisation and regulation of the oil palm (Elaeis guineensis) stearoyl-ACP desaturase genes. Journal of Oil Palm Research (Special Issue), 1–17
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Sambanthamurthi, R., Othman, A., and Ramli, U. S. (1999). Biochemical factors that control oil composition in the oil palm. Journal of Oil Palm Research (Special Issue), 24–33
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Sambanthamurthi, R., Parman, S. H., and Mohd. Noor, R. (1996). Oil palm (Elaeis guineensis) protoplasts: Isolation, culture and microcallus formation. Plant, Cell, Tissue and Organ Culture, 46(1), 35–41. https://doi.org/10.1007/BF00039694
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Sambanthamurthi, R., Oo, K. C., and Parman, S. H. (1995). Factors affecting lipase activity in Elaeis guineensis mesocarp. Plant Physiology and Biochemistry (France), 33, 353-359 *
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Chong, C. L., and Sambanthamurthi, R. (1993). Effects of mesocarp bruising on the rate of free fatty acid release in oil palm fruits. International Biodeterioration and Biodegradation, 31(1), 65–70. https://doi.org/10.1016/0964-8305(93)90015-T
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Sambanthamurthi, R., Let, C. C., Cheang, O. K., Huat, Y. K., and Rajan, P. (1991). Chilling-induced lipid hydrolysis in the oil palm (Elaeis guineensis) Mesocarp. Journal of Experimental Botany, 42(9), 1199–1205. https://doi.org/10.1093/jxb/42.9.1199 *
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Sambanthamurthi, R., Oo, K. C., and Ong, A. S. H. (1987). Lipid metabolism in oil palm (Elaeis guineensis and Elaeis oleifera) protoplasts. Plant Science, 5, 97–105 *
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Sambanthamurthi, R., Laverack, P. D., and Clarke, P. H. (1984). Lysine excretion by a mutant strain of Pseudomonas aeruginosa. FEMS Microbiology Letters, 23(1), 11–15. https://doi.org/10.1111/j.1574-6968.1984.tb01026.x
Patents
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Sambanthamurthi, R., Tan, Y. A. and Sundram, K. Treatment of vegetation liquors derived from oil-bearing fruit, for example from palm fruit, and products therefrom. US Patent No. 7,387,802; Malaysian Patent PI 9804378 (Granted as MY-134878-A) Indonesia # P-990892
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Ramli, U.S., Mohd Basri, W., Sambanthamurthi, R., Cheah, S.C., Syed Alwee, S.S.R., Abdullah, S.N.A., Parveez, G.K.A., Othman,A., Abdul Manaf, M.A., Omar, A.R., Aminudin,D., Abdul Masani, M.Y.A. Recombinant enzyme and uses thereof. US 7538204 B2, Malaysian Patent PI 20040179
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Tan, Y. A., Sambanthamurthi, R., Sundram, K. and Wahid, M. B. Palm Phenolics and Flavonoids as Potent Biological and Chemical Antioxidants for Applications in Foods and Edible Oils. Malaysian Patent Application PI 20070567 (Granted as MY-169539-A), International Applications : PCT/MY2008/000031; W00200903148 (Granted) (Indonesia);US (CIP) 15/225,469; EU 08741608.7 (Granted) (Europe EP2155001B1)
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Sambanthamurthi, R., Tan, Y. A. and Sundram, K. Botanical extracts from oil palm vegetation liquor cosmeceutical applications. Malaysian Patent Application PI 20070568 (Granted as MY-155276-A); International Application PCT/MY2008/000030; US 8,859,017 B2 (Granted); US 9,381,145 B2 (Granted); Indonesia (Granted P000038585); Europe 08741607.9 (In Allowance)
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Sundram, K., Sambanthamurthi, R., Tan, Y. A., Wahid, M. B., and Leow, S. S. Compounds extracted from palm oil mill effluent for the treatment of cancer, compositions thereof and methods therewith. Malaysian Patent Application PI 20070623 (Granted as MY-177206-A); International Patent Application PCT/MY2008/000034; World Patent Application Publication WO 2008/130216; Europe Patent Application Publication EP2148690 (Granted-EP 2148690 B1);US-Divisional 14/564,014 (Abandoned); Brazil 16090006547(BR PI0811416 - Granted); Indonesia W00200903279 (Granted); India 6878/DELNP/2009; Colombia 9129031 (Colombia)
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Sambanthamurthi, R., Sundram, K., Tan, Y. A. and Wahid, M. B. An antiviral composition. Malaysian Patent Application PI20071192 (Granted MY-184667-A); International Application: PCT/MY2008/000075; Chinese Patent CN101815516A (Granted); Europe Patent 2182937B1 (Granted); Brazil Patent Application BRPI0814725A2 (Granted); United States Patent US10130672B2 (Granted); Indonesia Granted Patent P000039812
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Balasundram, N. Sambanthamurthi, R., Sundram, K., Tan, Y. A. and Wahid, M. B., Samman, S. and Agar, N.S. A Botanical Extract from the Aqueous Stream of the Palm Oil Milling Process for the Prevention and Inhibition of Oxidative Stress and Haemolysis in Human Red Blood Cells. Malaysian Patent Application PI20071517 (Granted as MY-146110-A); International Application PCT/MY2008/000100 (Completed); United States Patent US8790722B2; Chinese Granted Patent CN101873863B; Brazil Patent Application BRPI0817037A2 (Granted); Europe Patent EP 2200625B1(Granted); Indonesia W00201000820 (Granted)
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Sambanthamurthi, R. and Tan, Y. A. An Antimicrobial Composition Based on Botanical Extracts from Oil Palm Vegetation Liquor. Malaysian Patent Application PI20072189 (Granted as MY-173858-A); International Application: PCT/MY2008/000177; United States-Divisional Patent US8557309B2 (Granted)
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Sambanthamurthi, R., Leow, S. S., Tan, Y. A., Sundram, K., and Wahid, M.B. Composition comprising oil palm phenolics for use in providing neuroprotective effects and cognitive-enhancement. Malaysian Patent Application PI20090368 (Granted as MY-158598-A); International Patent Application PCT/MY2010/000019; World Patent Application WO 2010/087693; United States Patent US9642389B2 (Granted); Europe Patent Application EP 2391375A4 ; Brazil Patent Application BRPI1007789A2; Indonesia Patent Application (W00201103011)
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Sambanthamurthi, R. and Tan, Y. A., Abeywardena, M., Sundram, K., Composition and Method for Improving Vascular Health. Malaysian Patent Application PI20091963 (Granted as MY-173655-A); International Application: PCT/MY2010/000096; Europe Patent EP 2440224B1(Granted); United States Patent US8771764B2 (Granted); United States Divisional Patent (US9759782B2); Brazil Patent Application BRPI1015432A2; Indonesia Patent Application W00201200064 (Granted IDP000039819)
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Hayes, K.C., Sundram, K., Sambanthamurthi, R. and Tan, Y. A. Methods for the Treatment or Prevention of Diabetes Mellitus and other Metabolic Imbalances. US2009/0252817A1 (Granted as US8071143 B2); WO2009146102A1; Japan Patent Application JP2011518131A; Australian Patent AU2009251568B2 (Granted) Malaysian Patent MY153112A (Granted); Denmark Patent DK2288364T3 (Granted); Europe Patent EP 2288364B1(Granted); Chinese Patent CN102088988A (Granted); Brazil Patent Application BRPI0911083A2; Spain Patent ES2474726T3 (Granted)
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Sambanthamurthi, R., Tan, Y. A., Sundram, K., Wahid, M. B., and Leow, S.S. Anti-obesity and anti-dyslipidaemic effects of oil palm phenolics in preventing atherosclerosis and cardiovascular disease. Malaysia Patent Application PI2010000060 (Granted MY-185582-A); World Patent Application Publication WO2011084046; Europe Patent Application Publication EP2521560 (Granted) ; United States Patent Application Publication US20130184355 (Abandoned); US-Divisional Granted Patent US9931368B2; US-Continuation Patent Application 15/898,477 (Granted US 11000564 B2); Indonesia Patent Application W00201203174; Brazil Patent Application 112012016850-9
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Che Idris, C. A., Balasundram,N., Sambanthamurthi, R., Tan, Y. A., Sundram, K. and Wahid, M. B. A composition for use in the prevention and treatment for cardiovascular diseases. Malaysian Patent Application PI 20092024 (Granted as MY-161839-A); International Application : PCT/MY2010/00081 ; Europe Patent EP 2432486B1 (Granted); Brazil Application BRPI1015468A2; United States Patent US8778419B2(Granted); US-Divisional Granted Patent US9,839,662B2; CN102573869A(Granted); Indonesia Granted Patent P000039001
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Sambandan, T.G., Rha, C.K., Sinskey, A.J., Sambanthamurthi, R., Tan, Y. A., Sundram, K. and Wahid, M. B. Composition comprising caffeoylshikimic acids, protocatechuic acid, hydroxybenzoic acid and their derivatives and method preparation thereof. Malaysian Patent Application Pl20092142 (Granted as MY-170986-A); International Application: PCT/MY2010/000089; Brazil Patent Application BRPI1015441A2; Chinese Patent Application CN102448925B (Granted) Europe Patent EP2435397B1 (Granted); United States Patent US9962421B2(Granted); US Continuation Granted Patent US10,603,348B2; US Continuation Patent Application 16/805,626; Indonesia Granted Patent IDP000045542
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Sambandan, T.G., Rha, C.K., Sinskey, A.J., Sambanthamurthi, R., Tan, Y. A., Sundram, K. and Wahid, M. B. Compositions comprising shikimic acid obtained from oil palm based materials and method of producing thereof. Malaysian Patent Application PI 2010002835 (Granted as MY-160702-A); International Application: PCT/MY2011/000097; Europe Patent EP 2582654B1(Granted); United States Patent US9963415B2(Granted); US Continuation Granted Patent US 10,308,582B2; Brazil Patent Application BR112012031900-0
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Kang, H., Rha, C.K., Sinskey, A.J., Sambanthamurthi, R., Tan, Y. A., Sundram, K. and Wahid, M. B. Compositions comprising extracts obtained from oil palm based materials for providing anti-inflammatory effects and method of producing thereof . Malaysian Patent Application PI 2010005402 (Granted as MY-165513-A). International Application Number: PCT/MY2011/000234
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Hafezi-Mogadham, A., Sambanthamurthi, R. and Tan, Y. A. Compositions comprising extracts or materials derived from palm oil vegetation liquor for inhibition of vision loss due to angiogenesis and method of preparation thereof. Malaysian Patent Application PI 2011002220; International Application Number: PCT/MY2012/000102 ; Europe Patent EP EP2709643B1(Granted); Brazil Patent Application BR112013029577A2 (Granted); US Continuation Granted Patent US10,183,054B2; Indonesia Granted Application W00201305446
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Rasid, O.A., Parveez, G.K.A., Singh, R. and Sambanthamurthi, R. Compositions and method for modification of oil palm carotenoid content. Malaysian Patent Application PI2011003297 (Granted MY-179778-A)
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Sambanthamurthi, R., Tan, Y. A., Fairus, S., Che Idris, C. A., Leow, S. S., Mohd Jamil, E., Wan Saridah, W. O., Jabariah, M. A., and Mohd Sofian, M. I. Novel bioactive compound obtained from oil palm base materials. Malaysia Patent Application PI2012700505 (Granted MY-185831-A); World Patent Application Publication WO2014017900; United States Patent US9919020B2 (Granted); Brazil Patent Application BR112015001856A2 (Granted); Europe Patent Application EP 2877193A4; Thailand Patent Application 1501000423; Indonesia Patent Application P00201500661
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Masani, M.Y.A., Gundula Noll, Parveez, G. K. A., Prüfer, D. and Sambanthamurthi, R. Plant regeneration from protoplast derived from oil palm suspension cultures. Malaysian Patent Application PI 2012700558 (Granted); International Application: PCT/MY2013/000145 ; Costa Rica Patent Application CR20150135A (Granted)
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Gupta, S.V., Khosla, P., Xiangming, J.I., Sambanthamurthi, R. and Tan, Y. A. Anti-proliferative effects of palm vegetation liquor and extracts thereof in preventing pancreatic cancer. Malaysian Patent Application PI 2012701146 (Granted); International Application: PCT/MY2013/000228; Brazil Patent Application BR112015013958A2; China Patent Application CN104981248A; United States Patent US10342844B2 (Granted)
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Sambanthamurthi, R., Tan, Y. A., Sundram, K. Process of extraction of phytochemicals from vegetation liquors of oil-bearing fruits. Malaysian Patent Application PI2013001990; United States Patent Application US20160107123A1 (Abandoned); Brazil Application No BR112015030113A (Granted); PCT Application WO2014193218A2; Indonesia Patent Application P00201508824; India Patent Application 11791/DELNP/2015
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Sambanthamurthi, R. and Tan, Y. A., Md Ali, J. and Wan Omar, W.S. Composition with inhibitory effect on viral integrase activity. Malaysian Patent Application PI2013700282 (Granted); International Application: PCT/MY2014/000019
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Weinberg, R.P., Rha, C.K., Sinskey, A.J., Tan, Y. A. and Sambanthamurthi, R. Protective effects of OPVL and OPP on Alzheimer’s Disease. Malaysian Patent Application PI2013003739 (Granted MY-179462-A); International Application: PCT/MY2014/000252; United States Patent Application US20160250274A1 US Continuation Application 16/507,838; Brazil Granted Patent BR0080351; Europe Patent Application EP 3057437A4 ( Granted-EP3057437); Indonesia Granted Application P00201603135; India Patent Application 201617016372
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Singh, R., Low, E.T.L., Ooi, L C-L., Ong-Abdullah, M., Nookiah, R., Sambanthamurthi, R., Smith, S.W., Lakey, N., Martienssen, R.A., Ordway, J.M. and Hogan, M. Gene controlling shell phenotype in oil palm. Malaysian Granted Patent MY-154507-A; European Patent Application EP 13863862.3 (Granted); Brazil Patent Application BR 112014013591-6; China Granted Patent Application CN104486940B; US Granted Patent No. US9,481,889B2; U.S. Divisional Patent No. 10,633,715 B2 (Granted); Indonesia Granted Patent P00201300174; Indonesia Divisional Patent Application P00201809053; Colombia Patent Application CO14130026 (Granted - #34038)
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Singh, R., Low, E.T.L., Ooi, L C-L., Abdul Rahim, R., Ong-Abdullah, M., Jayanthi, N., Rosli,R., Mohd Amin, H., Nookiah,R., Chan, K-L., Norazah, A., Sambanthamurthi, R., Martienssen, R.A., Smith, S.W., Lakey, N., Van Brunt, A., Ordway, J.M., Hogan, M. and Wang, C. Gene controlling color phenotype in oil palm. Malaysia Patent App. PI 2014700730 (Granted) United States Patent Application US20140302497A1 (Granted); WO2014168759A1; Europe Patent Application EP 2984179A4 (Granted); Singapore Patent Application SG10201708207PA (Granted); Costa Rica Patent Application CR20150609A (Granted); Indonesia Patent App P00201401789 (Granted)
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Singh, R., Low, E.T.L., Ooi, L C-L., Ong-Abdullah, M., Nookiah, R., Sambanthamurthi, R., Ordway, J.M., Lakey, N., Smith, S. W., Martienssen, R.A., Hogan, M. Expression of SEP-like genes for identifying and controlling palm plant shell phenotypes. PCT Application Publication WO2015010131A2; Malaysian Patent Application No, PI 2014701992 (Granted MY- 182698-A); Malaysian Divisional Patent No. PI 2016701520 (Granted-MY-184171-A) & PI 2016701519 (Granted- MY-185348-A)
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Singh, R., Low, E.T.L., Ooi, L C-L., Ong-Abdullah, M., Nookiah, R., Sambanthamurthi, R., Ordway, J.M., Lakey, N., Smith, S. W., Martienssen, R.A. and Hogan, M. Detection method for shell alleles. Indonesian Granted Patent (ID P000056085); Malaysian Granted Patent (MY-156871-A)
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Ordway, J.M., Singh, R., Low, E.T.L., Ooi, L C-L., Ong-Abdullah, M., Nookiah, R., Sambanthamurthi, R., Van Brunt, A., Budiman, M.A., Smith, S. W., Lakey, N. and Martienssen, R.A. MADS-box domain alleles for controlling shell phenotype in palm. WO2016205240A2; Malaysia Patent Application No. PI2017704802; Malaysia Divisional Patent Application No. PI2021001245; Indonesia Patent Application P00201708995 (Granted); Indonesia Divisional Patent Application No. P00202100434; Indonesia Divisional Patent Application No. P00202102636 & P00202102632; Thailand Patent Application No. TH 1701007452; Singapore Patent Application No. SG 10201912026Y; Costa Rican Application No. CR20180032A; Chinese Patent Application CN201680047538.5A (Granted); Brazil Patent Application BR112017027201A2; Europe Patent Application EP16812254.7A (Granted EP3307763B1); United States Patent Application US15/580,645 (Granted US10905061B2); US Divisional Application 17/131,384; US Divisional Colombian Application CO2018000194A2 (Granted-Patent #3802); India Patent Application No. IN201717047145 (Granted #403907)
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Sambandan, T.G., Rha, C.K., Sinskey, A.J., Vhoi, W.Y. Ravigadevi Sambanthamurthi, Tan Yew Ai. Process for carrier free spray drying of oil palm phenolics using a spray dryer. Malaysian Patent Application PI2015703238 (Granted)
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Sambandan, T.G., Rha, C.K., Sinskey, A.J., Sambanthamurthi, R. and Tan, Y.A. Antioxidant, anti-inflammatory compositions and uses thereof. Malaysian Patent Application PI2015703272 (Granted); United States Patent Application US15/462433 (Granted-US11033596B2); Chinese Patent Application 201780000807.7; France Patent Application FR 17 52236 (Granted-FR3063904); United Kingdom Patent Application GB1704250.8 (Granted)
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Koledova,V.V., Weinberg,R.P., Rha, C.K., Sinskey, A.J., Sambanthamurthi, R. and Tan, Y.A. Oil palm phenolics composition for the protection of humans, organs, cells and tissues against the injurious effects of exposure to ionizing radiation. Malaysian Patent Application PI2015704862; PCT/MY2016/000088 (International PCT Application); United States Patent Application US 16/067,130 (Abandoned); United States Divisional Application 16/853,696 (Abandoned);; ID Patent Application P00201805650 (Granted); Australian Patent Application AU 2016380627 ; Mexico Patent Application MX/A/2018/008211; United Kingdom GB 1812351.3 (Granted)
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Ong-Abdullah, M., Ooi, S.E., Low, E.T.L., Singh, R., Nookiah, R., Sambanthamurthi, R., Jiang, N., Steven W. Smith, Lakey, N.D., Martienssen, R., Ordway, J. and Hogan, M. Mantle phenotype detection in palm. United States Patent Application US20150315662 A1 (Granted as US9984200 B2); PCT/US2015/028646
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Osborne, A.E., Wangh, L.J., Hayes, K.C. and Sambanthamurthi, R. Treatment of DNA damage and mitochondrial dysfunction using palm fruit juice. US20160000854A1; Australian Patent Application AU2014214847A (Granted);United States Patent Application US14/766,215 (Granted); Eurasian Patent Application EA201591476A; Japanese Patent Application JP2015557070A (Granted); EP Patent Application EP14749028.8A (Granted);PCT Application WO2014124140A1
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Koledova,V.V., Weinberg,R.P., Rha, C.K., Sinskey, A.J., Sambanthamurthi, R. Aqueous botanical extract from palm oil plant comprising a method and composition for increasing the levels of tyrosine hydroxylase in the mammalian brain, and thus increasing catecholamine biosynthesis resulting in higher levels of dopamine, norepinephrine and epinephrine, among other catecholamines, in the brain. Provisional Patent Application US62/571,937 refiled as in #40
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Leow, S.S., Sambanthamurthi, R. and Hayes, K.C. Composition for delaying ageing process and increasing longevity in a subject and methods thereof. Malaysian Patent Application PI2018700929; PCT Patent Application PCT/MY2019/050017; EP Patent Application EP 19764659.0; United States Patent Application 16/979,154; Indonesia Patent Application P00202009039
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Conlon, M., Sambanthamurthi, R., Tan, Y. A., Syed Fairus, S.A.B. and Abeywardena, M. Composition comprising oil palm phenolics for use in the treatment and prevention of colon diseases and for promoting and maintaining gut and general health. Malaysian Patent Application PI2018702907; PCT Patent Application PCT/MY2019/050043; United States Patent Application 17,279,053
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Sinskey, A.J., Rha, C.K., Sambandan, T.G., Sambanthamurthi, R., Artamonova, A., De Angelo, J. and Ohashi, K. Beverage compositions comprising oil palm phenolics and palm fruit juice. US Provisional Application 62847342; EFS ID 36001419
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Sinskey, A.J., Rha, C.K., Sambandan, T.G., Sambanthamurthi, R. and Artamonova, A. Composition and method for modifying characteristics of edible consumables. US Provisional Application 62847340; EFS ID 36001402 (Item #38 & #39 filed and merged in Current US Non-Provisional Application 17/321,382; Title: COMPOSITION AND METHOD FOR MODIFYING CHARACTERISTICS OF EDIBLE CONSUMABLES).
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Koledova,V.V.,Weinberg, R.P., Rha, C.K., Sinskey, A.J., Hayes, K.C., Sambanthamurthi, R. Schneider, K.C., Artamanova, A. and Leow, S.S. Composition(s) for increasing tyrosine hydroxylase levels and improving brain health Malaysian Patent Application PI2019006896; PCT Application PCT/MY2020/050165; United States 17/782,953
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Leow, S.S., Fairus, S. and Sambanthamurthi, R. Inhibition of cholinesterases by palm fruit bioactives. Malaysian Patent Application PI 2020005106; PCT Application PCT/MY2021/050079
Other Journals
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The Nexus of Biodiversity Conservation and Sustainable Socioeconomic Development in Southeast Asia. Published by Academy of Sciences Malaysia in collaboration with Campaign for Nature 2022
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Strategic Paper on Precision Biodiversity (2020)
Prepared by Academy of Sciences Special Interest Group on Precision Biodiversity.
ISBN 978-983-2915-54-6
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Sambanthamurthi, R. ( 2020). Technology push for the plantation industry. The Planter 96
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MALAYSIA 2050 FLAGSHIP STUDY: Science & Technology Foresight Malaysia 2050 Emerging Science Engineering and Technology (ESET) Study. Academy of Sciences Malaysia 2017. Published by: Academy of Sciences Malaysia. I provided input for Biotechnology based on my appointment as Biotechnology Working Group Field Expert and Chairperson of the Biotechnology Working Group
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Lakey, N.D., Ordway, J.M., Jiang,N., Smith, S.W., Favello, A., Ooi, L. C. L., Singh, R., Nookiah, R., Low, E.T.L., Ong-Abdullah, M. and Sambanthamurthi, R. (2017). Increasing oil palm industry profit, Malaysian gross national income and government tax revenue with breakthrough DNA tests. The Planter Vol.93 (1093) 273-279
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Mohamad Arif, A.M., Izawati, A.M.D., Zubaidah, R., Masani, M.Y.A., Safiza, M., Lim, F.H., Nurniwalis, A.W., Rasid, O.A., Sambanthamurthi, R., Parveez, G.K.A. (2017). Biotechnology for diversification and improved resilience of the oil palm. The Planter, 93(1093): 237-249
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Sambanthamurthi, R. (2017). Guest Editorial: Reaping the fruits of biotechnology. The Planter Vol.93 (1093) ( Special theme issue on Biotechnology)
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Low, E.T.L., Singh, R., Nookiah, R;, Ong-Abdullah, M., Ooi, L. C. L., Lakey, N. D., Smith, S. W., Ordway, J.M., and Sambanthamurthi, R. (2016). New frontiers for the oil palm industry through genome technology. The Planter Vol. 92 (1087): 701-710
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Ong-Abdullah, M., Ordway, J.M., Jiand, N., Ooi, S. E., Mokri, A., Kok, S.Y., Sarpan, N., Azimi N,. Hashim, A. T., Ishak, Z., Rosli, S. K., Nookiah, R., Singh, R., Low, E. T. L., Sachdeva, M., Smith, S. W., Lakey, N. D., Martienssen, R. A. and Sambanthamurthi, R. (2016). Tissue culture and epigenetics. The Planter Vol. 92 (1087): 741-749
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Sambanthamurthi, R. (2016). Guest Editorial : Sowing the seeds of revolution. The Planter Vol. 92 (1087): 685 ( Special theme issue on Gene Revolution)
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Abeywardena, M., Sambanthamurthi, R., Tan, Y.A., Sundram, K. (2013). Oil palm phenolics as a bioactive ingredient in promoting cardiovascular health. J Oil Palm Environ. Health 5, 38–48
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Sambanthamurthi, R., Akmar, S. N. A and Parveez, G. K. A. (2002). Genetic manipulation of the oil palm – challenges and prospects. The Planter, 78: 547-562
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Sambanthamurthi, R. (2002). Towards understanding and controlling abscission in the oil palm. Oil Palm Bulletin, 45: 16-22
MPOB Transfer of Technology Information Series
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Leow, S.S., Fairus, S. and Sambanthamurthi, R. (2018). Caco-2 cell monolayer in vitro screening tool for drug discovery and mechanistics: Protocols for culture. MPOB TS No. 177. MPOB Information Series 802, ISSN 1511-7871
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Singh, R., Low, E T L., Ooi, L C-L., Chan, P-L., Ong, P.W., Ong-Abdullah, M., Nookiah.R., Marjuni, M., Yaakub, Z., Abdul Manaf, M.A., and Sambanthamurthi, R. (2018). SureSawitTM True-To-Type - A high throughput universal single nucleotide polymorphism (SNP) panel for DNA fingerprinting, purity testing and origin verification in oil palm. MPOB TT No. 632. MPOB Information Series 780, ISSN 1511-7871
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Ong-Abdullah, M., Ordway, J.M., Nan J., Ooi, S.E ., Mokri, A., Nookiah, R., Singh, R., Low, E.T.L., Sachdeva, M., Smith, S W., Lakey,N., Sambanthamurthi, R., and Martienssen, R.A. (2016). SureSawitTM Karma - A diagnostic assay for clonal conformity. MPOB TS No. 156. MPOB Information Series 738, ISSN 1511-7871
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Singh, R., Ooi, L C-L., Low, E T L., Ong-Abdullah, M., Nagappan, J., Ting, N.C., Abdul Manaf, M A., Nookiah.R., and Sambanthamurthi, R (2015). SureSawitTM Vir - A diagnostic assay to predict colour of oil palm fruits. MPOB TT No. 568. MPOB Information Series 697, ISSN 1511-7871
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Masani, M.Y.A., Parveez, G. K. A., and Sambanthamurthi, R. (2014). Transient gene expression system utilising oil palm protoplasts. MPOB TS 135. MPOB Information Series 687 ISSN 1511-7871
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Singh, R., Low, E.T.L., Ooi, L.C-L., Ong-Abdullah, M., Abdul Manaf, M.A., Abd Rahman, R., Nookiah.R., and Sambanthamurthi, R. (2014). SureSawitTM Shell - A Diagnostic Assay to Predict Oil Palm Fruit Forms. MPOB TT No. MPOB Information Series 656 ISSN 1511-7871
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Rasid, O. A., Parveez G. K A. Singh R., and Sambanthamurthi R. ( 2011). Lycopene cyclase genes for modification of carotenoid content. MPOB TT No. 480, MPOB Information Series 553, ISSN 1511-787
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Sambanthamurthi, R. Rha, C.K., Sinskey, A. J., Sambandan, T. G., Tan, Y.A. and Wahid, M.Y. (2010). Oil palm phenolics as a source of shikimic acid - an MPOB-MIT collaboration. MPOB TT No. 450, MPOB Information Series 506, ISSN 1511-787
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Maizura, I., Kushairi, A., Mohd Din, A., Noh, A., Marhalil, M., Wong Y.T. and Sambanthamurthi, R. (2008). PS13: Breeding populations selected for low lipase. MPOB TT No. 400. MPOB Information Series 425, ISSN 1511-7871
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Ramli, U.S., Sambanthamurthi, R., Cheah, S.C., Syed Alwee, S.S.R., Rasid, O. A., Abdullah, S.N.A., Parveez G. K A., Abdul Manaf, M.A., Abrizah, Othman, A., Masani, M.Y.A., Zulfazly, A and Wahid, M.B (2004). Beta-ketoacyl ACP Synthase II (KAS II). MPOB TT No. 219. MPOB Information Series 226, ISSN 1511-7871
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Sambanthamurthi, R. and Kushairi, A.D. (2002). Selection for lipase activity in the oil palm. MPOB TT No. 141. MPOB Information Series 158, ISSN 1511-7871
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Sambanthamurthi, R., Tan, Y.A. and Sundram, K. (2001). A novel process for the production of water-soluble antioxidants with potential nutraceutical applications from palm oil mill effluent (POME). MPOB TT No. 97, MPOB Information Series 112, ISSN 1511-7871
Book Chapters
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Masani, M.Y.A., Parveez, G.K.A., Noll, G., Mohd Al Akmarul Fizree, M.D.P., Sambanthamurthi, R. and Pruefer, D. Protoplast isolation and transformation in oil palm. In Protoplast Technology. (This book is currently in the queue of Springer publication)
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2.Sambanthamurthi, R., Ng. M.H. and Choo, Y.M. (2018). Bioactive compounds in oil palm. In Achieving sustainable cultivation of oil palm. Volume 2 pp.167-202. doi: 10.19103/AS.2017.0018.20 (Ed. Rival A.) Cambridge : Burleigh Dodds Series in Agricultural Science, 2
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Parveez, G.K.A., Omar, A.R., Tarmizi, A.H., Zamzuri, I., Samsul, K.R. and Sambanthamurthi, R. (2012). Tissue culture and genetic engineering. In Palm Oil: Production, Processing, Characterization and Uses pp.87-135. (Eds. Akoh, C; Ping, T C and Lai, O.M. ). AOCS press
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Parveez, G.K.A., Omar, A.R., and Sambanthamurthi, R. (2011). Genetic engineering of oil palm. In Further Advances In Oil Palm Research (2000-2010) pp.141-201 (Eds. Wahid, M. B. et. al.)
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Parveez, G.K.A., Abrizah, O., Ramli, U.S., Sambanthamurthi, R. Masani, M.Y.A., Tarmizi, A.H., Kushairi, A. and Mohd Basri, W. (2010). Improving value of oil palm using genetic engineering. In Biocatalysis and Biomolecular Engineering (Ed. Ching, T.H.)
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Sambanthamurthi, R., Singh, R., Parveez, G.K.A., Meilina O.A. Kushairi, A.D. (2009).Opportunities for the oil palm via breeding and biotechnology. In Breeding Plantation Tree Crops: Tropical Species. pp 377-421 (Eds.Jain, S.M. Priyadarshan, P.M.) Springer Publication.
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Parveez, G.K.A and Sambanthamurthi, R. (2005). Genetic enhancement and modification of oil crops: possibilities, problems and limitation. In Healthful Lipids pp 508-525 (Eds. Akoh, C.C. and Lai O.M.) AOCS press
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Sambanthamurthi, R., Syed Alwee, S.S.R., and Parveez, G.K.A. (2005). Safety, regulatory aspects, and public acceptance of genetically modified lipids. In Healthful Lipids pp. 33-47. (Eds. Akoh, C.C. and Lai, O.M.) AOCS press.
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Sambanthamurthi, R., Nookiah, R. and Parman, S.H. (2000). Lipid catabolism : Complex lipid degradation. In Recent Advances in the Biochemistry of Plant Lipids. pp 769 (Eds. Harwood J.L. and Quinn P.J.) Portland Press London.
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Ramli, U.S. and Sambanthamurthi, R. (I996). -Keto acyl ACP synthase II in the oil palm (Elaeis guineensis) mesocarp. In Physiology, Biochemistry and Molecular Biology of Plant Lipids. pp570. (Eds. J.P. Williams, M.U. Khan and N.W. Lem.) Kluwer Academic Publishers.
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Sambanthamurthi, R. and Ohlrogge, J. B. (1996). Acetyl CoA carboxylase activity in the oil palm. In Physiology, Biochemistry and Molecular Biology of Plant Lipids pp.26. (Eds. J.P. Williams, M.U. Khan and N.W. Lem.) Kluwer Academic Publishers
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Cheah, S.C., Sambanthamurthi, R. A., Akmar, S. N., Othman. A, Arif, A.M.M., Ramli. U. S. and Parveez, G.K.A. (1994). Towards genetic engineering of oil palm (Elaeis guineensis Jacq.). In Plant Lipid Metabolism. pp 570-572 (Eds. J.C. Kader and P. Mazliak) Kluwer Academic Publishers.
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Sambanthamurthi, R., Oo, K.C. and Parman, S. H. (I994). Lipase activity in the oil palm (Elaeis guineensis) mesocarp. In Plant Lipid Metabolism. pp 555. (Eds. J.C. Kader and P. Mazliak) Kluwer Academic publishers
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Sambanthamurthi, R., and Oo, K.C. (1990). Thioesterase activity in oil palm (Elaeis guineensis) mesocarp. In Plant Lipid Biochemistry, Structure and Utilization pp 166-168. (Eds. P.J. Quinn and J.L. Harwood.) Portland Press Lt London
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Sambanthamurthi, R., and Oo, K.C. and Ong, A.S.H. (1987). Lipid biosynthesis in oil palm protoplasts. In Metabolism Structure And Function Of Plant Lipids pp 529-53 1. (Eds. P. Stumpf, B. Mudd and D. Nes.) Plenum Publishers