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Patents

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  1. Sambanthamurthi, R., Tan, Y. A. and Sundram, K. Treatment of vegetation liquors derived from oil-bearing fruit, for example from palm fruit, and products therefrom. US Patent No. 7,387,802; Malaysian Patent PI 9804378 (Granted as MY-134878-A) Indonesia # P-990892
     

  2. Ramli, U.S., Mohd Basri, W., Sambanthamurthi, R., Cheah, S.C., Syed Alwee, S.S.R., Abdullah, S.N.A., Parveez, G.K.A., Othman,A., Abdul Manaf, M.A., Omar, A.R., Aminudin,D.,  Abdul Masani, M.Y.A. Recombinant enzyme and uses thereof.  US 7538204 B2, Malaysian Patent PI 20040179
     

  3. Tan, Y. A., Sambanthamurthi, R., Sundram, K. and  Wahid, M. B.  Palm Phenolics and Flavonoids as Potent Biological and   Chemical  Antioxidants for Applications in Foods and Edible  Oils. Malaysian Patent Application PI 20070567 (Granted as MY-169539-A), International Applications : PCT/MY2008/000031; W00200903148 (Granted) (Indonesia);US (CIP) 15/225,469; EU 08741608.7 (Granted) (Europe EP2155001B1)
     

  4. Sambanthamurthi, R., Tan, Y. A. and Sundram, K. Botanical extracts from oil palm vegetation liquor cosmeceutical applications.  Malaysian Patent Application PI 20070568 (Granted as MY-155276-A); International Application PCT/MY2008/000030; US 8,859,017 B2 (Granted); US 9,381,145 B2 (Granted);  Indonesia (Granted P000038585); Europe 08741607.9 (In Allowance)
     

  5. Sundram, K., Sambanthamurthi, R., Tan, Y. A., Wahid, M. B., and  Leow, S. S. Compounds extracted from palm oil mill effluent for the treatment of cancer, compositions thereof and methods therewith. Malaysian Patent Application PI 20070623 (Granted as MY-177206-A); International Patent Application PCT/MY2008/000034; World Patent Application Publication WO 2008/130216; Europe Patent Application Publication EP2148690 (Granted-EP 2148690 B1);US-Divisional 14/564,014 (Abandoned); Brazil 16090006547(BR PI0811416 - Granted); Indonesia W00200903279 (Granted); India 6878/DELNP/2009; Colombia 9129031 (Colombia)
     

  6. Sambanthamurthi, R., Sundram, K., Tan, Y. A. and Wahid, M. B.  An antiviral composition. Malaysian Patent Application PI20071192 (Granted MY-184667-A); International Application: PCT/MY2008/000075; Chinese Patent CN101815516A (Granted); Europe Patent 2182937B1 (Granted); Brazil Patent Application BRPI0814725A2 (Granted); United States Patent US10130672B2 (Granted); Indonesia Granted Patent P000039812
     

  7. Balasundram, N.  Sambanthamurthi, R., Sundram, K., Tan, Y. A. and Wahid, M. B., Samman, S. and Agar, N.S.  A Botanical Extract from the Aqueous Stream of the Palm Oil Milling Process for the Prevention and Inhibition of Oxidative Stress and Haemolysis in Human Red Blood Cells.  Malaysian Patent Application PI20071517 (Granted as MY-146110-A); International Application PCT/MY2008/000100 (Completed); United States Patent  US8790722B2; Chinese Granted Patent CN101873863B; Brazil Patent Application BRPI0817037A2 (Granted); Europe Patent EP 2200625B1(Granted); Indonesia W00201000820 (Granted)
     

  8. Sambanthamurthi, R. and  Tan, Y. A.  An Antimicrobial Composition Based on Botanical Extracts from Oil Palm Vegetation Liquor. Malaysian Patent Application PI20072189 (Granted as MY-173858-A);  International Application: PCT/MY2008/000177; United States-Divisional Patent US8557309B2 (Granted)
     

  9. Sambanthamurthi, R., Leow, S. S., Tan, Y. A., Sundram, K., and  Wahid, M.B. Composition comprising oil palm phenolics for use in providing neuroprotective effects and cognitive-enhancement.  Malaysian Patent Application PI20090368 (Granted as MY-158598-A); International Patent Application PCT/MY2010/000019; World Patent Application WO 2010/087693; United States Patent US9642389B2 (Granted); Europe Patent Application EP 2391375A4 ; Brazil Patent Application BRPI1007789A2; Indonesia Patent Application (W00201103011)
     

  10. Sambanthamurthi, R. and  Tan, Y. A., Abeywardena, M., Sundram, K., Composition and Method for  Improving Vascular Health. Malaysian Patent Application PI20091963 (Granted as MY-173655-A); International Application: PCT/MY2010/000096; Europe Patent EP 2440224B1(Granted); United States Patent US8771764B2 (Granted); United States Divisional Patent (US9759782B2); Brazil Patent Application BRPI1015432A2; Indonesia Patent Application W00201200064 (Granted IDP000039819)
     

  11. Hayes, K.C., Sundram, K., Sambanthamurthi, R. and Tan, Y. A.  Methods for the Treatment or Prevention of Diabetes Mellitus and other Metabolic Imbalances. US2009/0252817A1 (Granted as US8071143 B2); WO2009146102A1; Japan Patent Application JP2011518131A; Australian Patent AU2009251568B2 (Granted) Malaysian Patent MY153112A (Granted); Denmark Patent DK2288364T3 (Granted); Europe Patent EP 2288364B1(Granted); Chinese Patent CN102088988A (Granted); Brazil Patent Application BRPI0911083A2; Spain Patent ES2474726T3 (Granted)
     

  12. Sambanthamurthi, R., Tan, Y. A., Sundram, K., Wahid, M. B., and  Leow, S.S. Anti-obesity and anti-dyslipidaemic effects of oil palm phenolics in preventing atherosclerosis and cardiovascular disease. Malaysia Patent Application PI2010000060 (Granted MY-185582-A); World Patent Application Publication WO2011084046; Europe Patent Application Publication EP2521560 (Granted) ; United States Patent Application Publication US20130184355 (Abandoned); US-Divisional Granted Patent US9931368B2; US-Continuation Patent Application 15/898,477 (Granted US 11000564 B2); Indonesia Patent Application W00201203174; Brazil Patent Application 112012016850-9
     

  13. Che Idris, C. A., Balasundram,N.,  Sambanthamurthi, R., Tan, Y. A., Sundram, K. and Wahid, M. B.  A composition for use in the prevention and treatment for cardiovascular diseases. Malaysian Patent Application PI 20092024 (Granted as MY-161839-A); International Application : PCT/MY2010/00081 ; Europe Patent EP 2432486B1 (Granted); Brazil Application BRPI1015468A2; United States Patent US8778419B2(Granted); US-Divisional Granted Patent US9,839,662B2; CN102573869A(Granted); Indonesia Granted Patent P000039001
     

  14. Sambandan, T.G., Rha, C.K., Sinskey, A.J., Sambanthamurthi, R., Tan, Y. A., Sundram, K. and Wahid, M. B.  Composition   comprising   caffeoylshikimic acids, protocatechuic acid, hydroxybenzoic acid and their derivatives and method  preparation thereof.  Malaysian Patent Application Pl20092142 (Granted as MY-170986-A); International Application:  PCT/MY2010/000089; Brazil Patent Application BRPI1015441A2; Chinese Patent Application CN102448925B (Granted) Europe Patent EP2435397B1 (Granted); United States Patent US9962421B2(Granted); US Continuation Granted Patent US10,603,348B2; US Continuation Patent Application 16/805,626; Indonesia Granted Patent IDP000045542
     

  15. Sambandan, T.G., Rha, C.K., Sinskey, A.J., Sambanthamurthi, R., Tan, Y. A., Sundram, K. and Wahid, M. B.   Compositions comprising shikimic acid obtained from oil palm based materials and method of producing thereof. Malaysian Patent Application PI 2010002835 (Granted as MY-160702-A); International Application: PCT/MY2011/000097; Europe Patent EP 2582654B1(Granted); United States Patent US9963415B2(Granted); US Continuation Granted Patent US 10,308,582B2; Brazil Patent Application BR112012031900-0
     

  16. Kang, H., Rha, C.K., Sinskey, A.J., Sambanthamurthi, R., Tan, Y. A., Sundram, K. and Wahid, M. B.   Compositions comprising extracts obtained from oil palm based materials for providing anti-inflammatory effects and method of producing thereof . Malaysian Patent Application PI 2010005402 (Granted as MY-165513-A). International Application Number: PCT/MY2011/000234
     

  17. Hafezi-Mogadham, A.,  Sambanthamurthi, R. and  Tan, Y. A. Compositions comprising extracts or materials derived from palm oil vegetation liquor for inhibition of vision loss due to angiogenesis and method of preparation thereof. Malaysian Patent Application PI 2011002220; International Application Number: PCT/MY2012/000102 ; Europe Patent EP EP2709643B1(Granted); Brazil Patent Application BR112013029577A2 (Granted); US Continuation Granted Patent US10,183,054B2; Indonesia Granted Application W00201305446
     

  18. Rasid, O.A., Parveez, G.K.A., Singh, R. and Sambanthamurthi, R. Compositions and method for modification of oil palm carotenoid content. Malaysian Patent Application PI2011003297 (Granted MY-179778-A)
     

  19. Sambanthamurthi, R., Tan, Y. A., Fairus, S., Che Idris, C. A., Leow, S. S., Mohd Jamil, E., Wan Saridah, W. O., Jabariah, M. A., and  Mohd Sofian, M. I. Novel bioactive compound obtained from oil palm base materials. Malaysia Patent Application PI2012700505 (Granted MY-185831-A); World Patent Application Publication WO2014017900; United States Patent US9919020B2 (Granted); Brazil Patent Application BR112015001856A2 (Granted); Europe Patent Application EP 2877193A4; Thailand Patent Application 1501000423; Indonesia Patent Application P00201500661
     

  20. Masani, M.Y.A.,  Gundula Noll, Parveez, G. K. A., Prüfer, D. and Sambanthamurthi, R. Plant regeneration from protoplast derived from oil palm suspension cultures. Malaysian Patent Application PI 2012700558 (Granted); International Application: PCT/MY2013/000145 ; Costa Rica Patent Application CR20150135A (Granted)
     

  21. Gupta, S.V., Khosla, P., Xiangming, J.I., Sambanthamurthi, R. and Tan, Y. A. Anti-proliferative effects of palm vegetation liquor and extracts thereof in preventing pancreatic cancer. Malaysian Patent Application PI 2012701146 (Granted); International Application: PCT/MY2013/000228; Brazil Patent Application BR112015013958A2; China Patent Application CN104981248A; United States Patent US10342844B2 (Granted)
     

  22. Sambanthamurthi, R., Tan, Y. A., Sundram, K. Process of extraction of phytochemicals from vegetation liquors of oil-bearing fruits. Malaysian Patent Application PI2013001990; United States Patent Application US20160107123A1 (Abandoned); Brazil Application No BR112015030113A (Granted); PCT Application WO2014193218A2; Indonesia Patent Application P00201508824; India Patent Application 11791/DELNP/2015
     

  23. Sambanthamurthi, R. and Tan, Y. A., Md Ali, J. and Wan Omar, W.S. Composition with   inhibitory effect on viral integrase activity. Malaysian Patent Application PI2013700282 (Granted); International Application: PCT/MY2014/000019
     

  24. Weinberg, R.P.,  Rha, C.K., Sinskey, A.J., Tan, Y. A. and Sambanthamurthi, R. Protective effects of OPVL and OPP on Alzheimer’s Disease. Malaysian Patent Application PI2013003739 (Granted MY-179462-A); International Application: PCT/MY2014/000252; United States Patent Application US20160250274A1 US Continuation Application 16/507,838; Brazil Granted Patent BR0080351; Europe Patent Application EP 3057437A4 ( Granted-EP3057437); Indonesia Granted Application P00201603135; India Patent Application 201617016372
     

  25. Singh, R., Low, E.T.L., Ooi, L C-L., Ong-Abdullah, M., Nookiah, R., Sambanthamurthi, R., Smith, S.W., Lakey, N., Martienssen, R.A., Ordway, J.M. and Hogan, M. Gene controlling shell phenotype in oil palm. Malaysian Granted Patent MY-154507-A; European Patent Application EP 13863862.3 (Granted); Brazil Patent Application BR 112014013591-6; China Granted Patent Application CN104486940B; US Granted Patent No. US9,481,889B2; U.S. Divisional Patent No. 10,633,715 B2  (Granted); Indonesia Granted Patent P00201300174; Indonesia Divisional Patent Application P00201809053; Colombia Patent Application CO14130026 (Granted - #34038)
     

  26. Singh, R., Low, E.T.L., Ooi, L C-L., Abdul Rahim, R., Ong-Abdullah, M., Jayanthi, N., Rosli,R., Mohd Amin, H., Nookiah,R., Chan, K-L., Norazah, A., Sambanthamurthi, R., Martienssen, R.A., Smith, S.W., Lakey, N., Van Brunt, A., Ordway, J.M., Hogan, M. and Wang, C. Gene controlling  color phenotype in oil palm. Malaysia Patent App. PI 2014700730 (Granted) United States Patent Application US20140302497A1 (Granted); WO2014168759A1; Europe Patent Application EP 2984179A4 (Granted); Singapore Patent Application SG10201708207PA (Granted); Costa Rica Patent Application CR20150609A (Granted); Indonesia Patent App P00201401789 (Granted)
     

  27. Singh, R., Low, E.T.L., Ooi, L C-L., Ong-Abdullah, M., Nookiah, R., Sambanthamurthi, R., Ordway, J.M., Lakey, N., Smith, S. W., Martienssen, R.A., Hogan, M.  Expression of SEP-like genes for identifying and controlling palm plant shell phenotypes.  PCT Application Publication WO2015010131A2; Malaysian Patent Application No, PI 2014701992 (Granted MY- 182698-A); Malaysian Divisional Patent No. PI 2016701520 (Granted-MY-184171-A) & PI 2016701519 (Granted- MY-185348-A)
     

  28. Singh, R., Low, E.T.L., Ooi, L C-L., Ong-Abdullah, M., Nookiah, R., Sambanthamurthi, R., Ordway, J.M., Lakey, N., Smith, S. W., Martienssen, R.A. and Hogan, M.  Detection method for shell alleles.  Indonesian Granted Patent (ID P000056085); Malaysian Granted Patent (MY-156871-A)  
     

  29. Ordway, J.M., Singh, R., Low, E.T.L., Ooi, L C-L., Ong-Abdullah, M., Nookiah, R., Sambanthamurthi, R.,  Van Brunt, A., Budiman, M.A.,  Smith, S. W., Lakey, N. and  Martienssen, R.A. MADS-box domain alleles for controlling shell phenotype in palm.  WO2016205240A2; Malaysia Patent Application No. PI2017704802; Malaysia Divisional Patent Application No. PI2021001245; Indonesia Patent Application P00201708995 (Granted); Indonesia Divisional Patent Application No. P00202100434; Indonesia Divisional Patent Application No. P00202102636 & P00202102632;  Thailand Patent Application No. TH 1701007452; Singapore Patent Application No. SG 10201912026Y; Costa Rican Application No. CR20180032A; Chinese Patent Application CN201680047538.5A (Granted); Brazil Patent Application BR112017027201A2; Europe Patent Application EP16812254.7A (Granted EP3307763B1); United States Patent Application US15/580,645 (Granted US10905061B2); US Divisional Application 17/131,384; US Divisional  Colombian Application CO2018000194A2 (Granted-Patent #3802); India Patent Application No. IN201717047145 (Granted #403907)
     

  30. Sambandan, T.G., Rha, C.K., Sinskey, A.J., Vhoi, W.Y. Ravigadevi Sambanthamurthi, Tan Yew Ai.  Process for carrier free spray drying of oil palm phenolics using a spray dryer. Malaysian Patent Application PI2015703238 (Granted)
     

  31. Sambandan, T.G., Rha, C.K., Sinskey, A.J., Sambanthamurthi, R. and Tan, Y.A. Antioxidant, anti-inflammatory compositions and uses thereof. Malaysian Patent Application PI2015703272 (Granted); United States Patent Application US15/462433 (Granted-US11033596B2); Chinese Patent Application 201780000807.7;  France Patent Application FR 17 52236 (Granted-FR3063904); United Kingdom Patent Application GB1704250.8 (Granted)
     

  32. Koledova,V.V., Weinberg,R.P.,  Rha, C.K., Sinskey, A.J., Sambanthamurthi, R. and Tan, Y.A. Oil palm phenolics composition for the protection of humans, organs, cells and tissues against the injurious effects of exposure to ionizing radiation. Malaysian Patent Application PI2015704862; PCT/MY2016/000088 (International PCT Application); United States Patent Application US 16/067,130 (Abandoned); United States Divisional Application 16/853,696 (Abandoned);; ID Patent Application P00201805650 (Granted); Australian Patent Application AU 2016380627 ; Mexico Patent Application MX/A/2018/008211;  United Kingdom GB 1812351.3 (Granted)
     

  33. Ong-Abdullah, M., Ooi, S.E., Low, E.T.L., Singh, R., Nookiah, R., Sambanthamurthi, R., Jiang, N., Steven W. Smith, Lakey, N.D., Martienssen, R., Ordway, J. and Hogan, M. Mantle phenotype detection in palm. United States Patent Application US20150315662 A1 (Granted as US9984200 B2); PCT/US2015/028646
     

  34. Osborne, A.E., Wangh, L.J., Hayes, K.C. and Sambanthamurthi, R. Treatment of DNA damage and mitochondrial dysfunction using palm fruit juice. US20160000854A1; Australian Patent Application AU2014214847A (Granted);United States Patent Application US14/766,215 (Granted); Eurasian Patent Application EA201591476A; Japanese Patent Application JP2015557070A (Granted); EP Patent Application EP14749028.8A (Granted);PCT Application  WO2014124140A1
     

  35. Koledova,V.V., Weinberg,R.P.,  Rha, C.K., Sinskey, A.J., Sambanthamurthi, R. Aqueous botanical extract from palm oil plant comprising a method and composition for increasing the levels of tyrosine hydroxylase in the mammalian brain, and thus increasing catecholamine biosynthesis resulting in higher levels of dopamine, norepinephrine and epinephrine, among other catecholamines, in the brain. Provisional Patent Application US62/571,937 refiled as in #40
     

  36. Leow, S.S., Sambanthamurthi, R. and Hayes, K.C. Composition for delaying ageing process and increasing longevity in a subject and methods thereof. Malaysian Patent Application PI2018700929; PCT Patent Application PCT/MY2019/050017; EP Patent Application EP 19764659.0; United States Patent Application 16/979,154; Indonesia Patent Application P00202009039
     

  37. Conlon, M., Sambanthamurthi, R., Tan, Y. A., Syed Fairus, S.A.B. and Abeywardena, M. Composition comprising oil palm phenolics for use in the treatment and prevention of colon diseases and for promoting and maintaining gut and general health. Malaysian Patent Application PI2018702907; PCT Patent Application PCT/MY2019/050043; United States Patent Application 17,279,053
     

  38. Sinskey, A.J., Rha, C.K., Sambandan, T.G., Sambanthamurthi, R., Artamonova, A., De Angelo, J. and Ohashi, K. Beverage compositions comprising oil palm phenolics and palm fruit juice. US Provisional Application 62847342; EFS ID 36001419
     

  39. Sinskey, A.J., Rha, C.K., Sambandan, T.G., Sambanthamurthi, R. and  Artamonova, A. Composition and method for modifying characteristics of edible consumables.  US Provisional Application 62847340; EFS ID 36001402  (Item #38 & #39 filed and merged in Current US Non-Provisional Application 17/321,382; Title: COMPOSITION AND METHOD FOR MODIFYING CHARACTERISTICS OF EDIBLE CONSUMABLES).
     

  40. Koledova,V.V.,Weinberg, R.P.,  Rha, C.K., Sinskey, A.J., Hayes, K.C., Sambanthamurthi, R. Schneider, K.C., Artamanova, A. and Leow, S.S. Composition(s) for increasing tyrosine hydroxylase levels and improving brain health Malaysian Patent Application PI2019006896; PCT Application PCT/MY2020/050165; United States 17/782,953
     

  41. Leow, S.S., Fairus, S. and Sambanthamurthi, R. Inhibition of cholinesterases by palm fruit bioactives.  Malaysian Patent Application PI 2020005106; PCT Application  PCT/MY2021/050079

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